On my 2004 ford fusion my fob don't work the alarm sounds soon as I put the key into the door and turn it?

If I pull the central locking fuse out the alarm stops so it's drivable but was wondering what could be doing it as I was thought to believe if I put the key into the ignition the alarm should stop but it don't any ideas would be most appreciated

First check the fob. Most auto parts stores have a tester on the counter. If its good unlock the car door with the key. That should kill the alarm. Then turn the key on and off 8 times until the doors unlock themselves. Then push any button on the remote and it will reset to the car.