How much does it cost to replace and paint a quarter panel on a 2004 ford escape?

Answer please.

Replace? You mean welding in a new one? That gets pricey… Probably couple thousand bucks for everything.

Have you considered going to a salvage yard for old vehicles and finding the model that you have? Then take the quarter panel to a paint and body shop and have them color match it to the color of your vehicle, and they might even install it for you. This method will be far less expensive then if you went to a Ford Dealership and they ordered the part from the factory. I have gone to the salvage yards for parts many a time and I always get a good deal. And I save money by doing it this way.