1987 Ford F150 runs awful?

I've got a 1987 F150 with a 5 liter V8, and it just runs awful. I have checked for a leaky vacuum lines, leaky gaskets, chafed wires, and a whole bunch of other stuff. I have replaced distributor cap, spark plugs, spark plug wires, ignition coil, and ECU. It misfires badly, has a hard time starting sometimes, and will randomly stall while you're driving it. This happens every single time I drive it. From my experience, it sounds like it has a bad camshaft position sensor. Do these trucks even have that? What else could it be?

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The car is over thirty years old. Have you carried out a compression test? That's the first job to determine bore and head condition. If a cylinder is down on psi you need to take the head off and look for the cause. With the head(s) upside down on the bench test the valve sealing by pouring gas into all of the combustion chambers. The liquid should stay in place. If it drains away the seats need recutting or replacing and probably the valves and guides too. It's pointless replacing stuff at random like you have done, hoping you will hit on the faults. You have to work through a diagnosis first.

Replace the TFI module.

What was the condition of the plugs, or did you even bother? If you don't know, pull each one and check it now. This will usually give you an idea what is going on. Vacuum gauge will also tell you a lot. Finally a compression test. If equipped with a cam or crank sensor, if they were bad it probably wouldn't run. Though, I doubt it has a cam sensor.

Check timing belt and cam

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